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Hyperdense Capsule Sign at Noncontrast CT as an Indication for Middle Meningeal Artery Embolization for Nonacute Subdural Hematomas: A MAGIC-MT TrialPost Hoc Analysis 期刊论文

编号：

B431275F264EC58474D662DA7E2DB069
作者：

Weng, Ruiyuan#^[1]Su, Jiabin^[1];Zhou, Shengjun^[2];Yang, Heng^[1];Jiang, Hanqiang^[1];Gao, Xinjie^[1];Gao, Chao^[1];Hao, Jiheng(郝继恒)^[3]Zhang, Meng(张萌)^[3]Wang, Dengliang^[4];Jiang, Zhiwen^[1];Fei, Yuchao^[1];Yu, Zeran^[1];Liu, Wanyu^[1];Ni, Wei*^[1]Gu, Yuxiang^[1];
语种：

英文
期刊：

RADIOLOGY ISSN：0033-8419 2026 年 320 卷 1 期 ; JUL
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摘要：

Background: Hematoma recurrence and progression remain common challenges in nonacute subdural hematomas (SDHs). The understanding of indications for middle meningeal artery embolization (MMAE) is limited. Purpose: To investigate the utility of the hyperdense capsule sign (HDCS) at noncontrast CT for identifying potential candidates for MMAE for nonacute SDH. Materials and Methods: In this post hoc analysis of the MAGIC-MT randomized controlled trial (September 2022 to December 2023) comparing adjunctive MMAE and usual care, participants were grouped by HDCS presence or absence at noncontrast CT. The primary outcome was symptomatic recurrence or progression of SDH. The Cochran-Mantel-Haenszel chi 2 test, propensity score matching (PSM), multivariable analysis, and P value for interaction were used for subgroup comparisons. Results: Among 697 participants included in this analysis (median age, 69 years [IQR, 61-74 years]; 575 male participants), 444 (63.7%) showed HDCS presence. Primary outcome incidence was lower in the embolization versus usual-care group among participants with the HDCS (5.0% vs 12.0%, P = .009; after PSM: 4.1% vs 11.2%, P = .04) but not among those without the HDCS (9.4% vs 5.6%, P = .24; after PSM: 10.3% vs 5.0%, P = .13), with an interaction between MMAE and HDCS presence (P = .01; after PSM: P = .01). The proportion of participants experiencing a serious adverse event was lower in the embolization versus usual-care group among those with the HDCS (5.9% vs 15.1%, P = .002; after PSM: 5.8% vs 15.5%, P = .02) but not among those without the HDCS (8.7% vs 5.6%, P = .34; after PSM: 9.4% vs 5.8%, P = .30), with a significant interaction (P = .01; after PSM: P = .02). Conclusion: For participants with nonacute SDH, the presence of the HDCS was associated with a lower rate of recurrence or progression among those who underwent MMAE compared with those receiving usual care. HDCS may potentially help identify candidates for MMAE for nonacute SDH.
推荐引用方式
GB/T 7714：

Weng Ruiyuan,Su Jiabin,Zhou Shengjun, et al. Hyperdense Capsule Sign at Noncontrast CT as an Indication for Middle Meningeal Artery Embolization for Nonacute Subdural Hematomas: A MAGIC-MT TrialPost Hoc Analysis [J].RADIOLOGY,2026,320(1).
APA：

Weng Ruiyuan,Su Jiabin,Zhou Shengjun,Yang Heng,&Gu Yuxiang.(2026).Hyperdense Capsule Sign at Noncontrast CT as an Indication for Middle Meningeal Artery Embolization for Nonacute Subdural Hematomas: A MAGIC-MT TrialPost Hoc Analysis .RADIOLOGY,320(1).
MLA：

Weng Ruiyuan, et al. "Hyperdense Capsule Sign at Noncontrast CT as an Indication for Middle Meningeal Artery Embolization for Nonacute Subdural Hematomas: A MAGIC-MT TrialPost Hoc Analysis" .RADIOLOGY 320,1(2026).
入库时间：

8/27/2026 9:14:06 PM
更新时间：

8/27/2026 9:14:06 PM

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