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Association of the C-Reactive Protein-Triglyceride-Glucose Index with Stroke-Heart Syndrome and Clinical Prognosis in Patients Undergoing Endovascular Treatment.  期刊论文  

  • 编号:
    E96757DAB38DB90ACD37E24D9CE562D8
  • 作者:
    Chen Wenjie[1];Bai Xuesong[2];Wang Tao[2];Jiao Liqun[2];Zhang Liyong(张利勇)[3]Li Hong[1];
  • 地址:
    (Chen Wenjie)Department of Cardiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China.,(Bai Xuesong)Department of Neurosurgery, Beijing Xuan-Wu Hospital, Capital Medical University, Beijing 100053, China.,(Wang Tao)Department of Neurosurgery, Beijing Xuan-Wu Hospital, Capital Medical University, Beijing 100053, China.,(Jiao Liqun)Department of Neurosurgery, Beijing Xuan-Wu Hospital, Capital Medical University, Beijing 100053, China.,(Zhang Liyong)Department of Neurosurgery, Liaocheng People's Hospital, Shandong First Medical University, Liaocheng 252000, China.,(Li Hong)Department of Cardiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China.
  • 语种:
    英文
  • 期刊:
    Journal of cardiovascular development and disease ISSN:2308-3425 2026 年 13 卷 5 期 ; 2026-Apr-25
  • 收录:
  • 关键词:
  • 摘要:

    Stroke-heart syndrome (SHS), particularly acute myocardial injury, is a critical complication following acute ischemic stroke (AIS). The C-reactive protein-triglyceride-glucose index (CTI) integrates inflammatory and metabolic parameters but remains unexplored in the context of post-stroke cardiac complications. This study investigated whether CTI predicts cardiac injury patterns and 90-day clinical outcomes in AIS patients.;A two-center retrospective cohort study was conducted in AIS patients undergoing endovascular treatment (EVT). Cardiac troponin I (cTnI) trajectories were classified into: no injury, non-dynamic elevation, and dynamic elevation. The primary endpoint was poor functional status at 90 days (modified Rankin Scale [mRS] 3-6); the secondary endpoint was 90-day all-cause death.;Among 493 individuals (median age 69 years, 42% female), higher baseline CTI was associated with a greater likelihood of dynamic troponin elevation (adjusted odds ratio [aOR] per 1-unit increase = 1.56 (1.26-1.94); p < 0.001). Patients with dynamic elevation had significantly worse outcomes compared to those with no injury. Elevated CTI was an independent predictor of 90-day poor functional outcome (Q4: aOR = 3.04 (1.53-6.05); p < 0.001) and mortality (Q4: aOR = 2.82 (1.33-6.00); p = 0.007).;In EVT-treated AIS patients, the CTI is a predictor of SHS and adverse 90-day outcomes. This easily calculable index may help identify individuals at higher risk of cardiac complications after AIS.;

  • 推荐引用方式
    GB/T 7714:
    Chen Wenjie,Bai Xuesong,Wang Tao, et al. Association of the C-Reactive Protein-Triglyceride-Glucose Index with Stroke-Heart Syndrome and Clinical Prognosis in Patients Undergoing Endovascular Treatment. [J].Journal of cardiovascular development and disease,2026,13(5).
  • APA:
    Chen Wenjie,Bai Xuesong,Wang Tao,Jiao Liqun,&Li Hong.(2026).Association of the C-Reactive Protein-Triglyceride-Glucose Index with Stroke-Heart Syndrome and Clinical Prognosis in Patients Undergoing Endovascular Treatment. .Journal of cardiovascular development and disease,13(5).
  • MLA:
    Chen Wenjie, et al. "Association of the C-Reactive Protein-Triglyceride-Glucose Index with Stroke-Heart Syndrome and Clinical Prognosis in Patients Undergoing Endovascular Treatment." .Journal of cardiovascular development and disease 13,5(2026).
  • 入库时间:
    6/3/2026 9:48:36 PM
  • 更新时间:
    6/4/2026 1:58:12 AM
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